Elyse Catherine Keaton (b. Elyse Cateherine Donnelly) is a character in Family Ties. She is portrayed by Meredith Baxter-Birney. She is an architect working for both larger firms and independently throughout the series' run. She is the wife of Steven Keaton, the mother to Alex P. Keaton, Mallory Keaton, Jennifer Keaton, and Andrew Keaton. She is the daughter of Charlie and Kate Donnelly, as well as the oldest sister to Ned Donnelly and Michele.